「The Safety Efficacy And Pharmaceutical Quality Of Male Enhancement Nutraceuticals Bought Online: Truth Versus Claim」を編集中

<br>Objective: Nutraceutical products are widely used for their claimed therapeutic benefits. However, falsified or adulterated nutraceuticals present a major health threat to consumers. This study investigates the pharmaceutical quality, safety and anti-inflammatory effects of six male enhancement nutraceuticals that claim to be 100% natural. Methods: Three batches of six male enhancement products were tested to detect the presence and levels of adulterants via high-performance liquid chromatography (HPLC). The pharmaceutical quality of the selected nutraceuticals was tested with near infrared spectroscopy (NIR) and SeDeM. The cytotoxic effects of these products on HepG2 cells were determined through cell proliferation (XTT) and lactate dehydrogenase (LDH) cytotoxicity assays. Lastly, the in vitro inflammatory effects of these products were investigated using murine J774 macrophages through cytokine release analysis. Results: HPLC analysis detected the presence of sildenafil citrate, a vasodilator, and the active ingredient in Viagra and Revatio, in all batches of the products we analyzed. Amount of sildenafil citrate ranged from 0.45 mg to 51.85 mg among different batches.<br><br><br><br>NIR assessment showed inter- and intra-batch heterogeneity in product composition. Results of the XTT and LDH assays showed significant cytotoxic effects of the analyzed products. XTT analysis revealed that the viability of HepG2 treated with tested products varied from 27.57% to 41.43%. Interestingly, the male enhancement products also showed anti-inflammatory effects. Conclusion: Despite their labeling as 100% natural, all products tested in this study contained levels of sildenafil citrate, which was not reported on the packaging. There was a lack of pharmaceutical uniformity among products of the same batch and across different batches. Additionally,  [https://test.cuber.co.kr/onyeol/bbs/board.php?bo_table=free&wr_id=132351 Titan Rise Nutrition] the products we tested had cytotoxic effects. These study findings highlight the adulteration, poor quality and hazard of these nutraceuticals. Therefore, strict regulation of these products and standardization of the definition of nutraceuticals are urgently needed. Further, these falsely advertised [https://www.deviantart.com/search?q=products products] should be withdrawn from the market due to potential adverse effects on the health of their [https://www.medcheck-up.com/?s=consumers consumers].<br><br><br><br>What Is Body Fat Percentage? What Is a Good Body Fat Percentage for a Male? What Are the Risks of High Body Fat? What Are the Risks of Low Body Fat? What Is a Realistic Body Fat Percentage? You’ve almost certainly heard the term ‘body fat percentage’ before, whether in conversation in the gym changing room, marketing fodder for fitness transformations, or even in a Men’s Health article. With a little bit of know how, the measure can act not just as a motivator on your fitness journey, but better yet, a dependable marker of health. But that begs the question, what is a healthy body fat percentage? When starting on a fitness journey, the odds of you actually sticking to it has been shown to be only 33 per cent,' explains Josh Silverman, head of education at Third Space London. Unlike BMI, this measurement takes into account your lean mass as well as total weight.<br><br><br><br>Let’s chew the fat about body fat. Fun fact: due to it being so active in the body's functioning,  [http://pasarinko.zeroweb.kr/bbs/board.php?bo_table=notice&wr_id=7157701 Titan Rise Male Enhancement] fat is technically an organ. Far from being something to fear or vilify, fat is actually essential for human life. There are different types - brown,  [https://www.seono1.co.th/forum/index.php?action=profile;u=50995 Titan Rise Nutrition] white, subcutaneous, visceral - and each has its own function, for better or worse. Visceral fat and subcutaneous fat are the two we're going to focus on here. Visceral fat is stored around internal organs as a protective mechanism, explains Silverman. It’s the first fat that is usually used for fuel when you go on an exercise regime,' he says. This is why you might see the scales go down by your body appears to look the same for the first few weeks.' Visceral fat is the most dangerous kind, but thankfully, it’s also the easiest to lose. The less harmful stuff, subcutaneous fat, is the type that prevents your abs popping.<br>