「Background: Trauma Patients Frequently Receive Supplemental Oxygen」を編集中

<br>Background: Trauma patients frequently obtain supplemental oxygen, however its hemodynamic effects in blood loss are poorly understood. We studied the effects of oxygen on the hemodynamic response and tolerance to simulated blood loss in healthy volunteers. Methods: Fifteen wholesome volunteers have been exposed to simulated blood loss by decrease body unfavorable stress (LBNP) on two separate visits not less than 24 h apart. They were randomized to inhale 100% oxygen or medical air on go to 1, while inhaling the opposite on go to 2. To simulate progressive blood loss LBNP was elevated every 3 min in levels of 10 mmHg from 0 to eighty mmHg or  [https://45.76.249.136/index.php?title=User:WilliemaeDickins BloodVitals SPO2] until hemodynamic decompensation. Oxygen and air were delivered on a reservoired face mask at 15 L/min. The effect of oxygen in comparison with air on the adjustments in cardiac output, stroke volume and center cerebral artery blood velocity (MCAV) was examined with combined regression to account for repeated measurements inside subjects. The effect of oxygen compared to air on the tolerance to blood loss was measured as the time to hemodynamic decompensation in a shared frailty mannequin. Cardiac output was the primary consequence variable. Conclusions: We found no impact of oxygen in comparison with air on the adjustments in cardiac output, stroke volume or MCAV during simulated blood loss in healthy volunteers. However, oxygen had a favorable effect on the tolerance to simulated blood loss with fewer hemodynamic decompensations. Our findings recommend that supplemental oxygen does not adversely have an effect on the hemodynamic response to simulated blood loss.<br><br><br><br>Lindsay Curtis is a health & medical author in South Florida. 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