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The most frequently reported serious adverse events were cardiac (13.3% of patients) and vascular disorders (10.6% of patients) which may be related to comorbidities. SSRIs SSRIs which are antidepressant drugs, are often used to treat anxiety disorders. Rationale: Weight gain during treatment with antipsychotics is a prominent side-effect, especially with some second-generation antipsychotics, such as olanzapine and clozapine, and pharmacological treatments which ameliorate this side-effect are important to investigate. An "attempted cost per QALY" was calculated as being between $105,000 and $200,000, based on a difference of 0.01 in preliminary utility gain.<br><br><br> The PBAC noted that the sponsor claimed that cost per QALY is not meaningful and could not be reliably estimated. The net financial cost per year to the PBS (excluding co-payments) was estimated by the re-submission to be less than $10 million in Year 5, and lower than the estimate in the previous submission. The re-submission estimated the incremental cost per additional QALY gained to be between $105,000 and $200,000. The sponsor believes that when a treatment is as specific and localised as that with cilostazol, the cost per QALY is not the most appropriate measure of its worth. Always follow your doctor's advice for your specific situation. For specific advice or queries about using Tugain Solution, consult your doctor. Abbott Labs had a patent on a specific drug called Omnicef used to combat ear infections. The PBAC noted the results of a systematic review and meta-analysis of drug therapy for IC (Momsen et al 2009) which suggested that the highest benefit in terms of walking distance is obtained by treating patients with lipid lowering agents. 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Isotroin 20 Capsule is highly effective but requires careful monitoring due to potential side effects.<br>