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What Raises The Danger Of Thalassemia
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<br>Thalassemia is an inherited blood disorder that causes your physique to produce less hemoglobin than normal. Hemoglobin is a protein in pink blood cells that helps them carry oxygen to all parts of the body. Hemoglobin is fabricated from two sorts of protein chains known as alpha globin and beta globin. Thalassemia develops when defective genes forestall your physique from making the right amount of alpha globin or beta globin chains. When this occurs, pink blood cells cannot carry sufficient oxygen to your body’s organs and tissues. Should you inherit faulty hemoglobin genes from one mother or father however regular genes from the other, [https://dev.kirill-vorotov.com/margeneguyton3 BloodVitals SPO2] you might be called a "carrier." Carriers often don't have any indicators of illness or they could expertise mild anemia. However, [https://king-wifi.win/wiki/Apple_Watch_Series_6_Rumors:_Blood_Oxygen_Tracking_Performance_Improvements_Faster_WiFi_And_More BloodVitals device] they'll move the defective genes on to their kids. Should you inherit defective genes from each mother and father, your disease may be moderate to severe. The 2 types of thalassemia are alpha thalassemia and beta thalassemia. How does alpha thalassemia develop?<br><br><br><br>You want four genes (two from each father or mother) to make enough alpha globin protein chains. If one or more of the genes is lacking, you'll have alpha thalassemia, which implies your physique doesn't make sufficient alpha globin protein. If you’re only lacking one gene, you are a "silent" provider. This means you will not have any signs of sickness. If you’re missing two genes, you have alpha thalassemia trait (also referred to as alpha thalassemia minor). This means you'll have mild signs of anemia. If you’re lacking three genes, you doubtless have hemoglobin H disease (which a blood check can detect). Any such thalassemia causes reasonable to severe anemia. Very rarely, a baby is missing all four genes. This condition is named alpha thalassemia major or hydrops fetalis. Babies who've hydrops fetalis normally die before or shortly after birth. In the image, the alpha globin genes are located on chromosome 16. A toddler inherits four alpha globin genes (two from each parent).<br><br><br><br>In this instance, the father is lacking two alpha globin genes and the mother is lacking one alpha globin gene. Each youngster has a 25% probability of inheriting two missing genes and [https://the-qrcode.com/berenicecatala BloodVitals health] two normal genes (thalassemia trait), three missing genes and [https://menwiki.men/wiki/Glucose_Meter_Selection_Monitoring BloodVitals device] one normal gene (hemoglobin H disease), 4 normal genes (no anemia), or one missing gene and three regular genes (silent service). How does beta thalassemia develop? You want two genes (one from every father or mother) to make enough beta globin protein chains. If one or each of these genes are altered, you’ll have beta thalassemia. This means that your physique won’t make enough beta globin protein. If you have one altered gene, you’re a service. This condition is known as beta thalassemia trait or beta thalassemia minor. It causes mild anemia symptoms. If both genes are altered, you’ll have beta thalassemia intermedia or beta thalassemia major [https://ashwoodvalleywiki.com/index.php?title=Why_Don_t_We_Live_Underground BloodVitals device] (also called Cooley's anemia). The intermedia type of the disorder causes reasonable anemia. The major form causes serious anemia signs.<br><br><br><br>Within the image, the beta globin gene is positioned on chromosome 11. A baby inherits two beta globin genes (one from every dad or mum). In this instance, every father or mother has one altered beta globin gene. Each youngster has a 25% probability of inheriting two normal genes (no anemia), a 50% likelihood of inheriting one altered gene and one regular gene (beta thalassemia trait), or a 25% chance of inheriting two altered genes (beta thalassemia major). What raises the chance of thalassemia? You may be more prone to have thalassemia primarily based on your loved ones history and genetics and your race or ethnicity. In case your parents have mutations within the alpha globin or beta globin genes, or in other genes that have an effect on the alpha or beta globin proteins chains, [https://srv482333.hstgr.cloud/index.php/Self-Measured_Blood_Pressure_SMBP_Monitoring BloodVitals device] then you'll be able to inherit thalassemia. If someone in your family has thalassemia, you could also be a carrier. Carriers can go the condition on to their children.<br><br><br><br>Thalassemia occurs most frequently among individuals of South Asian, Italian, Greek, [https://gl.ignite-vision.com/meielvis043922 BloodVitals SPO2] Middle Eastern, and African descent. People of South Asian descent are more likely than different teams to have at the least two missing alpha globin genes, [https://www.ebersbach.org/index.php?title=Blood_Oxygen_SPO2_Calculator BloodVitals device] inflicting extra severe alpha thalassemia (hemoglobin H disease or alpha thalassemia major). Can thalassemia be prevented? Since thalassemia is attributable to modifications (mutations) in genes, there is no means to stop it. People who have no idea whether they carry a faulty gene that can cause thalassemia can ask their healthcare supplier for a blood test. Couples who are planning to have youngsters and [https://hub.theciu.vn/franziskaburns BloodVitals device] know that they're at risk of getting a baby with thalassemia might want to fulfill with a genetic counselor. A genetic counselor can reply questions on the danger and clarify the choices that are available. If you're pregnant and you or your accomplice has a household history of thalassemia, your provider may additionally advocate prenatal testing. Prenatal testing is done using a pattern of amniotic fluid, the liquid in the sac surrounding a growing embryo, or of tissue taken from the placenta, the organ that attaches the umbilical cord to the mother’s womb. Testing earlier than start is protected and will be finished as early as 8 to 10 weeks into the pregnancy.<br>
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