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2025年9月24日 (水) 13:08時点におけるIWNStepanie (トーク | 投稿記録)による版
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Like in 2017's Nike-sponsored occasion, Kipchoge's 1:Fifty nine doesn't count as an official world report. This is because it wasn't a part of an formally sanctioned race and used pacemakers that rotated in and out of the run. The attempt was organised by chemical company Ineos, which has links to fracking and is owned by the UK's richest man, Jim Ratcliffe. But environmental politics aside, there was some critical science behind Kipchoge's run. Here's how he did it. Before we get into what helped Kipchoge cross the road in 1:59:40, it's value pausing and contemplating how ridiculously quick this is. To interrupt it down, it is under a 2:50 min/km pace for forty two kilometres or around 4:34.5 per mile for every of the 26 miles. Each of Kipchoge's kilometres were between 2:48min/km and 2:52min/km - that means at no point did he fall behind the target 1:59:59 pace. Those figures may not imply much after they're viewed on their own but when in comparison with common humans, they're ridiculous.

Late-onset Pompe disease (GSD-II) additionally has calf hypertrophy and hypothyroidism as comorbidities. Poor food regimen and malabsorption diseases (comparable to celiac disease) might result in malnutrition of important vitamins vital for glycogen metabolism inside the muscle cells. Malnutrition typically presents with systemic signs, but in rare cases will be limited to myopathy. Vitamin D deficiency myopathy (also called osteomalic myopathy because of the interplay between vitamin D and calcium) ends in muscle weakness, predominantly of the proximal muscles; with muscle biopsy exhibiting abnormal glycogen accumulation, atrophy of kind II (quick-twitch/glycolytic) muscle fibres, and diminished calcium uptake by the sarcoplasmic reticulum (needed for muscle contraction). Exercise-induced, electrically silent, muscle cramping and stiffness (transient muscle contractures or "pseudomyotonia") are seen not only in GSD types V, VII, IXd, X, XI, XII, and XIII, but additionally in Brody illness, Rippling muscle illness types 1 and 2, and CAV3-related hyperCKemia (Elevated serum creatine phosphokinase).